Now that the 2025 NFL Schedule has been released, many experts are trying to predict which teams will have the most regular season wins. See which teams the oddsmakers believe in below.
Buffalo Bills, Baltimore Ravens Favored To Have Great Regular Seasons
The Buffalo Bills and Baltimore Ravens have been excellent regular-season teams under Josh Allen and Lamar Jackson.
Since the start of the 2022 season, the two teams have combined for 72 wins.
If Patrick Mahomes and the Kansas City Chiefs didn’t play in the AFC, the Bills and Ravens would likely be trading Super Bowl appearances over the past few seasons.
The Bills (+350) are slightly favored over the Ravens (+500) to have the most wins. Part of that is because the Bills play in the AFC East, an inferior division compared to the Ravens.
The Bills have six games against the New York Jets, New England Patriots, and Miami Dolphins. All three of those teams missed the postseason in 2024.
Meanwhile, the Ravens play in the AFC North, which features multiple games against the Pittsburgh Steelers, Cleveland Browns, and Cincinnati Bengals.
The Ravens previously held the best record in 2023 (13-4).
2025 NFL Regular Season: Team With Most Wins
| Team | Odds |
|---|---|
| Buffalo Bills | +350 |
| Baltimore Ravens | +500 |
| Kansas City Chiefs | +800 |
| Philadelphia Eagles | +850 |
| San Francisco 49ers | +1200 |
| Tampa Bay Buccaneers | +1800 |
| Detroit Lions | +1800 |
| Los Angeles Rams | +2000 |
| Denver Broncos | +2000 |
| Washington Commanders | +2200 |
| Green Bay Packers | +2200 |
| Minnesota Vikings | +2500 |
| Los Angeles Chargers | +2500 |
| Cincinnati Bengals | +2800 |
| New England Patriots | +4500 |
| Arizona Cardinals | +4500 |
| Houston Texans | +5000 |
| Seattle Seahawks | +5500 |
| Pittsburgh Steelers | +6600 |
| Chicago Bears | +6600 |
| Jacksonville Jaguars | +8000 |
| Dallas Cowboys | +8000 |
| Atlanta Falcons | +8000 |
| Miami Dolphins | +20000 |
| Indianapolis Colts | +20000 |
| Tennessee Titans | +25000 |
| Las Vegas Raiders | +25000 |
| Carolina Panthers | +25000 |
| New York Jets | +40000 |
| New York Giants | +40000 |
| New Orleans Saints | +50000 |
| Cleveland Browns | +70000 |
Odds via BetOnline on 5/23/25 at 4:45 p.m. ET.
You can never count out the Kansas City Chiefs (+800).
The Kansas City Chiefs finished with a franchise record 15 wins in 2024. The only other team to match Kansas City’s win total last year was the Detroit Lions (15-2).
The defending Super Bowl champion Philadelphia Eagles (+850) and the San Francisco 49ers (+1200) round out the top five.
Keep an eye on the Niners, who have the easiest schedule by a wide margin, according to Sharp Football Analysis.
