Movies
Novocaine Opening Weekend Box Office Predictions & Odds
Dan is a multifaceted content creator who specializes in sports, pop culture, and entertainment. His entertainment work has been featured on Digital Trends, where he has interviewed Brendan Fraser, Jamie Lee Curtis, Alison Brie, Adam DeVine, Sadie Sink, Chris O'Dowd, Machine Gun Kelly, and Frank Grillo. Dan's entertainment work has also been featured on Coming Soon, Hidden Remote, and WatchMojo. Dan's other passion in life revolves around sports, graduating from Marist College with a degree in Sports Communication and Journalism. From columns about the latest in New York sports to gambling predictions, Dan continues to find success in written and broadcast journalism. Previous written work can be found at Unafraid Show, while broadcast clips can be seen on WAVE.tv and CBS Sports.
Get to know Dan Girolamo betterPublished12 Mar 2025
Jack Quaid is a man who feels no pain in the action comedy Novocaine. Below are the predictions and odds for Novocaine’s opening weekend box office.
What Is Novocaine About?
Nathan “Nate” Caine is a banker who describes himself as a “regular guy with a regular job.” However, Nate has a special condition called congenital insensitivity to pain (CIP). In simplest terms, Nate doesn’t feel pain.
Nate catches a lucky break when he meets Sherry (Amber Midthunder), the girl of his dreams.
The night after spending time with Sherry, bank robbers infiltrate his work. To make matters worse, the thieves take Sherry as a hostage.
Refusing to wait for the police, Nate goes on the offensive and looks for Sherry.
“Would you wait around for someone else to save her, or would you do it yourself?” It’s time for Nate to save the day, despite being ridiculously unqualified.
Novocaine also stars Ray Nicholson, Jacob Batalon, Betty Gabriel, and Matt Walsh.
The filmmaking duo of Dan Berk and Robert Olsen direct Novocaine from a screenplay by Lars Jacobson. Producers include Joby Harold, Tory Tunnell, Drew Simon, Julian Rosenberg, and Matt Schwartz.
Paramount Pictures will release Novocaine in theaters on March 14, 2025.
Novocaine Opening Weekend Box Office Odds
| Novocaine Opening Weekend Box Office: Domestic | Odds |
|---|---|
| Less than $7 million | +809 |
| $7 million-$9 million | +122 |
| $9 million-$11 million | +133 |
| Over $11 million | +3233 |
Odds via Polymarket on 3/12/25 at 6:15 p.m. ET
Novocaine is eyeing a $10 million opening (+133) this weekend. A double-digit opening would be an excellent start for a film with an $18 million.
Novocaine will face competition for the top spot at the domestic box office from Mickey 17, Bong Joon-ho’s follow-up to Parasite.
Mickey 17 opened to $19.1 million last weekend.
Other movies opening this weekend include Black Bag, Steven Soderbergh’s spy thriller starring Michael Fassbender and Cate Blanchett, and Opus, a thriller with Ayo Edebiri and John Malkovich.
