The best game of NFL Week 1 is set for Sunday Night Football. Here are the storylines, picks, and best bets for the Baltimore Ravens taking on the Buffalo Bills.
Ravens vs. Bills: Game Information
Today's Forecast: COLD FRONT. 🥶#BillsMafia | #GoBills pic.twitter.com/3vpDJWi8rM
— Buffalo Bills (@BuffaloBills) August 28, 2025
- 🏈 Game: Ravens vs. Bills
- 🕗 Time: 8:20 p.m. ET
- 🏟 Location: Highmark Stadium — Orchard Park, New York
- 📺 TV Channel: NBC
- 💻 Live Stream: Peacock
Top Storyline: AFC Divisional Round Rematch
Fitted for Week 1❕@Invisalign | Win a jersey: https://t.co/gQLKpvU84I pic.twitter.com/JC7XbhoGIu
— Baltimore Ravens (@Ravens) September 4, 2025
The Bills eliminated the Ravens from the playoffs in the Divisional Round on January 19, 2025.
Less than eight months later, the Ravens return to the scene of the crime to exact their revenge.
After trading first-quarter touchdowns, the Bills outscored the Ravens 14-3 to end the first half, thanks to two costly turnovers by Jackson.
The game will be remembered for two Mark Andrews mistakes. The Ravens’ tight end fumbled in the fourth quarter and dropped the game-tying two-point conversion.
The Bills won the game 27-25.
Ravens vs. Bills: Picks and Best Bets
Bills +1.5 (-115)
Is this the year Jackson or Josh Allen gets to the Super Bowl?
The two superstar quarterbacks have won MVP trophies and brought their teams to AFC Championship games. However, the two can’t get over the hump and reach the Super Bowl. (Thank you, Patrick Mahomes.)
If the line stays put, the Ravens will have been favored in 19 consecutive games, the longest active streak in the NFL.
John Harbaugh is an excellent coach, especially when he has extra time to prepare. Harbaugh is 12-5 ATS in Week 1.
The Ravens continue to boast one of the league’s best rosters, and they strengthened their secondary by adding Jaire Alexander and Chidobe Awuzie.
Had the Ravens been the underdog, they would have been the play. However, the Bills getting points at home won’t happen again. The Bills are 22-3 at home since 2022, and Allen is still the MVP.
Allen makes enough plays late to pull out a close win.
Lamar Jackson Over 1.5 Touchdown Passes (-130)
In gambling, there is no such thing as a lock. However, Jackson has been on a tear when it comes to his passing touchdowns prop.
Jackson has hit the over on his touchdown passes in 14 of his last 16 games.
The weakest part of the Bills’ defense is its secondary. Maxwell Hairston is on injured reserve, and Tre’Davious White and Christian Benford are battling groin injuries.
Jackson could have a field day through the air on Sunday night.
