The 2025 NFL season is now upon us, and fans and bettors are racing to their respective sportsbooks to place their wagers on the Week 1 action. One of the sites that is gaining popularity this year is PrizePicks, utilizing their “More Or Less” format and catering to a fantasy-style betting system.
But PrizePicks has its own noticeable limitations, which is where the offshore sportsbooks and betting sites come into play. Below, we’ll list some of the best options when it comes to betting apps that allow you to get in on the NFL action, and we’ll even walk you through a step-by-step process on how to sign up and qualify for big bonus bets and promos.
How To Bet On The NFL
- Click here to join BetUS
- Register using a valid email address
- Claim a 125% bonus, up to $2,625
- Place your NFL bets right away
5 Best Sportsbooks With NFL Betting Offers
- BetUS — 125% Bonus, Up To $2,625 On Your First 3 Deposits
- BetWhale — 200% Welcome Bonus, Up To $6,000
- BetOnline — $250 In Free NFL Bets
- BetNow — $250 Cash Bonus For The NFL Season
- MyBookie — 100% Deposit Bonus, Up to $500
1. BetUS — 125% Bonus, Up To $2,625 On Your First 3 Deposits
BetUS has built a strong name in the online betting space, delivering a full lineup of options that includes spreads, totals, player props, and futures. The platform makes banking quick and straightforward, so players can spend more time wagering and less time worrying about transactions.
With the 2025 NFL season just around the corner, players can tap into some of the site’s biggest offers. New members are welcomed with a 125% bonus spread across their first three deposits—worth up to $2,625 in added betting funds. Crypto users get an even better deal, scoring a 200% bonus that supercharges their bankroll from day one.
Why Sign Up For BetUS?
- Wide range of betting markets with competitive odds
- Multiple promotions for new and existing users
- NFL betting pools with huge cash prizes
- 125% deposit bonus up to $2,625 on your first 3 deposits
2. BetWhale — 200% Welcome Bonus, Up To $6,000
BetWhale is diving into the 2025 NFL season with a splash, giving bettors a huge welcome offer—an impressive 200% deposit match that can deliver up to $6,000 in bonus cash.
Beyond the big bonuses, BetWhale is turning heads with its sharp NFL lines and consistently competitive odds, quickly carving out space among the industry’s heavyweights. Though still relatively new, its rapid rise and player-friendly features position it as a serious option for football fans looking to get in on the action this season.
Why Sign Up For BetWhale?
- Largest betting bonus for Week 1
- Competitive odds on all NFL games
- Instant deposits and fast withdrawals
- 200% bonus up to $6,000
3. BetOnline — $250 In Free NFL Bets
BetOnline has long been a favorite among NFL bettors, but its reach stretches well beyond the gridiron. The sportsbook covers everything from global sporting events and smaller niche leagues to politics and entertainment, giving players an expansive betting menu. Banking is equally straightforward, with smooth deposits and quick, reliable withdrawals.
As the 2025 NFL season kicks off, players can claim a welcome bonus of up to $250 in free bets. Signing up is simple—just an email registration unlocks full access to BetOnline’s wide range of wagering opportunities.
Why Sign Up For BetOnline?
- Competitive odds, player props, and same-game parlays
- $1 million NFL Survivor Contest
- $250 first deposit bonus for new users
- Bonus offers with no hidden rollover requirements
4. BetNow — $250 Cash Bonus for the NFL Season
BetNow has earned its reputation for keeping things simple, delivering a platform that feels accessible to newcomers while still satisfying experienced bettors. As the 2025 NFL season gets underway, users can enjoy competitive odds along with promotions designed to stretch the value of every wager.
A key highlight is BetNow’s 2% rebate on all sports bets, ensuring players get something back on every play. New members are also welcomed with a 25% bonus worth up to $250 in extra funds. With its clean design and player-friendly features, BetNow stands out as a smart pick for bettors who want both convenience and added rewards this season.
Why Sign Up For BetNow?
- No fees on deposits or payouts
- 2% rebate on losses
- Free-to-enter NFL contest with $20,000 grand prize
- $250 welcome bonus offer
5. MyBookie — 100% Deposit Bonus, Up to $500
MyBookie has secured its spot as a top choice in the online betting world, thanks to a sleek design, easy navigation, and a range of attention-grabbing promotions. Bettors gearing up for the 2025 NFL season can take advantage of a 100% first-deposit match, giving new users up to $500 in bonus funds to start their action.
It also supports modern banking preferences, including full cryptocurrency transactions, while ensuring fast and reliable withdrawals. With its combination of user-friendly design, solid security, and rewarding bonuses, MyBookie continues to be a go-to option for NFL fans looking to get the most out of their wagers this season.
Why Sign Up For MyBookie?
- Sharp odds with low vig maximize profit
- Simple, intuitive platform for fast betting
- Wide markets covering all NFL matchups
- $500 first deposit bonus for new users
NFL 2025 Week 1 Odds
Here are the point spreads for all of the NFL Week 1 games to kick off the 2025 regular season.
- Cowboys @ Eagles (-9)
- Chiefs (-3) @ Chargers
- Steelers (-2.5) @ Jets
- Dolphins (PK) @ Colts
- Panthers @ Jaguars (-3)
- Giants @ Commanders (-6)
- Bengals (-5) @ Browns
- Raiders @ Patriots (-2.5)
- Cardinals (-6.5) @ Saints
- Buccaneers (-2.5) @ Falcons
- Titans @ Broncos (-9)
- 49ers (-2.5) @ Seahawks
- Lions @ Packers (-2.5)
- Texans @ Rams (-3)
- Ravens (PK) @ Bills
- Vikings (-2) @ Bears
NFL 2025 Week 1 Predictions & Best Bets
Best Bet: 49ers (-2.5) vs. Seahawks
The 49ers have the softest schedule that the NFL has seen in quite some time, but they’ll get things started off with a road divisional matchup against the rival Seahawks. San Francisco has won 3 of its last 4 season openers, and have defeated the Seahawks in 6 of their last 7 meetings. Look for the trends to both continue and for the 49ers to cover the 2.5-point spread.
Upset Pick: Jets (+2.5) vs. Steelers
The New York Jets are under a new regime for 2025, having parted ways with Aaron Rodgers and their entire coaching staff during the offseason. But Rodgers comes back into town as a member of the Pittsburgh Steelers, who have their own expectations to live up to. Many are predicting that Pittsburgh’s new venture will be a failure with Rodgers at the helm, and things could get ugly if they lose on the road in Week 1.
