Colorado head coach Deion Sanders revealed Monday that he battled bladder cancer during the offseason.
Deion Sanders Provides Cancer Update
Tune in at 11AM MT to watch Coach Prime’s Press Conference
🖥️: https://t.co/JQDj2N45Sj pic.twitter.com/vgicQN0OBz
— Colorado Buffaloes Football (@CUBuffsFootball) July 28, 2025
Sanders, who is the head coach of the University of Colorado football team, recently faced his toughest opponent to date: cancer.
During Monday’s press conference, Sanders revealed that he had undergone surgery to remove his bladder after doctors found a tumor. Sanders described the illness as a “very high-risk, noninvasive bladder cancer.”
University of Colorado football coach Deion Sanders announced Monday that he had undergone surgery to remove his bladder after doctors discovered a tumor there.
Dr. Janet Kukreja, director of urological oncology at the University of Colorado Cancer Center, said that the surgery was a success. Sanders has no more traces of cancer, meaning “Prime Time” will coach the Buffaloes this season.
Speculation had been building about Sanders’ deteriorating health this offseason. Besides an appearance at Big 13 media day, Sanders had remained awfully quiet this offseason. He’s missed multiple football camps at Colorado due to his health issues.
This is not the first time Sanders has dealt with health issues while coaching. In June 2023, Sanders experienced significant blood clots in his leg that required amputation on two of his toes.
"You have no idea how good God has been to me."
Deion Sanders got emotional after revealing he is cured from cancer. pic.twitter.com/3VDTX0HMFH
— SportsCenter (@SportsCenter) July 28, 2025
Deion Sanders Enters Year Three At Colorado
Let's learn to LOVE like we may not get another opportunity to do so provided we choose the right people to LOVE! Love is so special it's so unique & so real. God is LOVE & his LOVE is unconditional. Let's stop judging, stop hating & Let LOVE have its way! #CoachPrime
— COACH PRIME (@DeionSanders) July 28, 2025
With Sanders back in the saddle at Colorado, he will face uncharted territory as a head coach.
Sanders must find a new quarterback to replace his son, Shedeur, who went to the Cleveland Browns in April’s draft. Ever since Sanders started coaching in high school, Shedeur has been his quarterback.
After a shaky 4-7 campaign in 2023, Sanders led the Buffaloes to a 9-4 record, ending with a loss to BYU in the Alamo Bowl. Shedeur won Big 12 Offensive Player of the Year and passed for 4,134 yards and 37 touchdowns while completing 74.0% of his passes.
Sanders must always replace the reigning Heisman Trophy winner, Travis Hunter, who will play wide receiver and cornerback for the Jacksonville Jaguars. Sanders’ other son, Shilo, is also a safety with the Tampa Bay Buccaneers.
Colorado’s quarterback situation will come down to freshman Julian Lewis, a five-star recruit, and Kaidon Salter, who transfers in from Liberty.
Colorado opens the season on Aug. 29 against Georgia Tech.
