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Making it in professional football isn’t easy. It takes hard work, dedication, and skill to make the full-time 52-man roster on one of the 32 NFL teams. Surprisingly, several pairs of brothers have gone on to NFL greatness, so today we look at the most famous siblings to ever step on the gridiron.

Eli and Peyton Manning

You can’t start off a list of famous NFL brothers without including Peyton and Eli Manning. Both were No. 1 overall picks and two-time Super Bowl Champions. A five-time MVP, Peyton Manning was named to the Pro Bowl 14 times before retiring in 2015. Little brother Eli is still the starter for the New York Giants as they try to make it back to the playoffs.

Jason and Travis Kelce

Travis Kelce is arguably the best tight end in football. Since being drafted in 2013, he’s been a consistent threat for the Kansas City Chiefs. The 29-year-old has 80-plus receptions for each of the last three seasons and had a career-high 103 for 1,336 yards and 10 touchdowns. As a bonus, he’s pretty fun at weddings, too.

Since 2011, big brother Jason Kelce has been a mainstay for the Philadelphia Eagles offensive line. Considered one of the league’s most dependable centers, the 31-year-old helped protect Nick Foles in the Eagles’ upset of Super Bowl 51.

J. J. Watt, Derek Watt, and T.J. Watt

J. J. Watt is already considered one of the greatest defensive players to ever step on a football field. The 30-year-old is a three-time NFL Defensive Player of the Year and has 92 career sacks. After two injury-riddled seasons in 2016 and 2017, he bounced back last season, putting up 16 sacks for the Texans.

Middle brother Derek Watt has played for the Chargers since 2016. And youngest brother T.J. Watt has become a force for the Steelers’ defensive front-seven since the absence of Ryan Shazier.

Michael Bennett and Martellus Bennett

The Bennett brothers are two of the most entertaining players in the league. Michael helped paved the way for the Seahawks’ dominant defensive run to a Super Bowl win over Peyton Manning’s Broncos. Younger brother Martellus Bennett retired in 2017 but finished his career with 30 touchdown receptions.

Ronde Barber and Tiki Barber

As a key player in the Tampa Bay Cover 2 defense, Ronde Barber was one of the most complete cornerbacks during his time in the NFL. He finished his career with eight defensive touchdowns and made the Pro Bowl four times. His twin brother Tiki was a threat running the ball and catching passes out of the backfield. He averaged over five yards per touch and amassed 15,632 total yards while playing his entire career for the Giants.

Chris Long and Kyle Long

With a Hall-of-Fame defensive lineman for a dad, the Long brothers had a good chance of making the NFL if they put the work in, which they did. The No. 2 pick of the 2008 draft, Chris was named the 2018 Walter Payton Man of the Year. He won back-to-back- Super Bowls to close out his career.

Younger brother Kyle’s career got off to a hot start as he earned three consecutive Pro Bowl selections. Unfortunately, injuries have plagued him during the last three seasons. We have to wonder if the Bears will place him on the trading block this season.