Real Betis vs Atletico Madrid Predictions, Betting Tips, Odds and Confirmed Lineups: Statistically Best Bet Builders

Real Betis vs Atletico Madrid in the Copa del Rey. Betting tips, predictions, odds and the statistically best bet builder bets ahead of Thursday night’s quarter-final clash.

Real Betis vs Atletico Madrid Betting Tips

Real Betis and Atletico Madrid go head-to-head in the Copa del Rey quarter-finals on Thursday.

The tie kicks off at 20:00 at Estadio La Cartuja and is shown live on ITV4 in the United Kingdom.

Betis head into the clash having secured a 2-1 triumph over Valencia in LaLiga on Sunday, seeing them climb up to fifth place in the table, just seven points adrift of the top four.

That result followed on from a 2-1 win over Feyenoord in the Europa League on Thursday evening, which saw them seal their spot in the competition’s last 16 with a top eight finish.

Subsequently, they are among the favourites at 9/1 in our latest Europa League winner odds.

To advance to this stage of the Copa del Rey, Betis have defeated Atletico Palme del Rio, Torrent, Real Murcia and Elche throughout the previous rounds.

Meanwhile, Atleti are third in the Spanish top-flight table after Saturday’s draw with Levante.

They have now won just one of their last four matches in all competitions (W1, D2, L1), with a shocking Champions League defeat by Bodo/Glimt preceding the weekend’s stalemate.

As a result of their loss to the Norwegian side, Diego Simeone’s side were unable to secure a top eight finish. This means they must take part in the playoffs before advancing to the last 16.

The Rojiblancos are rated at 33/1 in our Champions League winner odds market.

Atletico beat Atletico Baleares 3-2 and Deportivo 1-0 to reach the Copa del Rey quarter-finals.

Their recent head-to-head record against Betis bodes well for Antoine Griezmann and co ahead of this one too, as they have won each of their last two clashes against the Andalusian side.

Real Betis vs Atletico Madrid Lineups

Real Betis Predicted Lineup: Lopez; Ortiz, Llorente, Natan, Gomez; Deossa, Roca; Antony, Fornals, Ezzalzouli; Avila

Atletico Madrid Predicted Lineup: Oblak; Molina, Le Normand, Lenglet, Ruggeri; Baena, Koke, Cardoso, Gonzalez; Almada, Alvarez

Real Betis vs Atletico Madrid Bet Builder Tips

1. Julian Alvarez – Anytime Goalscorer

Alvarez leads Atletico’s attack and is heavily involved in both build-up and finishing phases.

He consistently finds space between defenders and is trusted to take chances when Atletico transition quickly.

Why: Central attacking role and high involvement make him Atletico’s primary goal threat.

2. Pablo Fornals – Over 0.5 Shots on Target

Fornals operates between the lines for Betis and frequently arrives in shooting positions around the edge of the box.

He is willing to test the goalkeeper when space opens rather than recycling possession.

Why: Advanced positioning and shooting intent make a shot on target likely.

3. Nelson Deossa to be Shown a Card

Deossa plays as Betis’ defensive midfielder and will be tasked with breaking up Atletico’s central attacks.

That role often involves tactical fouls when runners burst beyond the midfield line.

Why: Defensive responsibility and physical duels increase booking risk.

4. Antony – Over 1.5 Shots

Antony plays wide for Betis but regularly cuts inside onto his stronger foot to shoot.

He prefers to take on defenders directly, often ending moves himself rather than crossing.

Why: Direct dribbling style and shoot-first mentality point toward multiple attempts.

5. Match Total – Under 2.5 Shots

Atletico are typically controlled and compact in knockout matches, prioritising structure over risk.

With Betis facing a disciplined defensive block, clear chances may be limited.

Why: Cautious game state and knockout context favour a lower-scoring contest.

Real Betis vs Atletico Madrid Bet Builder

🎲 Bet Builder Odds @ 120/1

Real Betis vs Atletico Madrid Match Odds

Note: All odds on this page are subject to change