NFL Week 1 Schedule and Odds: Point Spreads and Totals for Every Game Including Bills-Rams, Packers-Vikings, and Buccaneers-Cowboys

Ladies and gentlemen, we made it.

It’s officially Week 1 of the 2022-23 NFL season, and we’ve got a loaded slate on deck to kick off the new year. On Thursday night, the reigning Super Bowl champion Los Angeles Rams will host the current Super Bowl favorite Buffalo Bills in the first game of the season. Then, the Sunday slate is headlined by Kansas City Chiefs-Arizona Cardinals, Green Bay Packers-Minnesota Vikings, and Tampa Bay Buccaneers-Dallas Cowboys.

So, with only a few days left until NFL football returns, let’s check out the Week 1 schedule and go through the betting odds for every game on the board.

NFL Week 1 schedule

Josh Allen looks on against the Rams.
Josh Allen of the Buffalo Bills looks on during a game against the Los Angeles Rams | Timothy T Ludwig/Getty Images

Thursday, September 8

8:20 p.m. ET

Buffalo Bills at Los Angeles Rams (NBC)

Sunday, September 11

1 p.m. ET

Pittsburgh Steelers at Cincinnati Bengals (CBS)
Philadelphia Eagles at Detroit Lions (FOX)
Indianapolis Colts at Houston Texans (CBS)
New Orleans Saints at Atlanta Falcons (FOX)
Baltimore Ravens at New York Jets (CBS)
New England Patriots at Miami Dolphins (CBS)
Cleveland Browns at Carolina Panthers (CBS)
San Francisco 49ers at Chicago Bears (FOX)
Jacksonville Jaguars at Washington Commanders (FOX)

4:25 p.m. ET

Las Vegas Raiders at Los Angeles Chargers (CBS)
New York Giants at Tennessee Titans (FOX)
Kansas City Chiefs at Arizona Cardinals (CBS)
Green Bay Packers at Minnesota Vikings (FOX)

8:20 p.m. ET

Tampa Bay Buccaneers at Dallas Cowboys (NBC)

Monday, September 12

8:15 p.m. ET

Denver Broncos at Seattle Seahawks (ESPN)

NFL Week 1 odds: Spreads and totals for every game

GamePoint SpreadTotal
Bills at RamsBills -2.552.5
Steelers at BengalsBengals -6.544.5
Eagles at LionsEagles -3.548.5
Colts at TexansColts -8.545.5
Saints at FalconsSaints -5.542.5
Ravens at JetsRavens -6.544.5
Patriots at DolphinsDolphins -2.546.5
Browns at PanthersPanthers -2.541.5
49ers at Bears49ers -6.541.5
Jaguars at CommandersCommanders -3.543.5
Raiders at ChargersChargers -3.552.5
Giants at TitansTitans -5.543.5
Chiefs at CardinalsChiefs -3.553.5
Packers at VikingsPackers -2.548.5
Buccaneers at CowboysBuccaneers -1.550.5
Broncos at SeahawksBroncos -6.542.5

All betting odds courtesy of FanDuel as of 9/5.

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