Quick-Fire Wednesday Champions League Betting Tips, Including Real Madrid vs Man City

See our quick-fire Champions League betting tips for all NINE games on Wednesday – including Club Brugge vs Arsenal and Real Madrid vs Manchester City. 

Champions League Betting Tips on Wednesday 10th December 2025 

The Champions League round six matches conclude on Wednesday night with NINE more matches – with two early 17:45pm kick-offs.

Fourth-placed PSG can move up the table if they see off Athletic Bilbao on the road – with just two more games after this week to go.

Table-toppers Arsenal make the trip to Club Brugge and are long odds-on to come back with all three points.

Another win for the Gunners could also see their Champions League winner betting odds of 4/1 shorten a tad.

But with the news of a Max Dowman ankle injury, Arsenal will be without their up-and-coming youngster for the game.

However, the tie of Wednesday is Real Madrid vs Manchester City – a Blue Moon win will see them move up into one of the coveted top eight slots.

You can see our quick-fire Champions League betting tips and match odds for ALL NINE matches below.

Qarabağ vs Ajax 17:45

These sides have only met once before, which came in the Europa League in October 2024 – that ended in an easy 3-0 away win for Ajax.

However, Ajax have struggled in the Champions League this season and are rock bottom of the table with zero points and five defeats.

Whereas Qarabag, who are in 21st (7 points) certainly have something to play for.

They also held Chelsea to a 2-2 draw last month in the Champions League.

Qarabag are ten games unbeaten in all comps coming into the game too – so with Ajax unlikely to put up much of a fight here a home win at 6/5 looks the call.

BEST BET: QARABAG WIN @ 6/5

Match Odds

Villarreal vs Copenhagen 17:45

This will be the first time these sides have met – so a bit of history being created here.

Both teams are flagging in this competition though – with Villarreal joint second from bottom with only a point (one draw).

While Copenhagen are 29th on four points (one win and a draw).

So with only three games left for them both, then wins will be crucial.

Therefore, with home advantage it’s hard to see beyond a win for Villarreal here.

The Spanish side are much better in front of their own fans – having lost only once at home this season (10 games) – which came to Man City.

Winning seven of those.

BEST BET: VILLARREAL WIN @ 4/9

Match Odds

Athletic Bilbao vs PSG 20:00

Two past clashes between these two sides, with a win each.

But these meetings came way back in 2011, so this will be the first time they’ve met in 14 years.

PSG will come into the game in fourth (12 points) and Bilboa back in 28th (4 points) and currently out of the play-off slots.

Bilboa head here in form though – having beaten Atl Madrid in the league last weekend and will know a win here will see them move into the play-off slots.

But PSG are also in rude form – beating Rennes 5-0 at home last Saturday and slammed Spurs 5-3 the last time they played in this competition.

Therefore, it’s hard to not see the visitors scoring – so BTTS (yes) looks the call here at 8/11.

BEST BET: BOTH TEAMS TO SCORE @ 8/11

Match Odds

Bayer Leverkusen vs Newcastle United 20:00

These two have faced-off twice in the past and it’s Newcastle that have the bragging rights, with two wins.

But these two clashes came back in 2003 in this competition, so a lot of water has passed under the bridge at both clubs since.

There is also only a point between the sides in the Champions League table, with Leverkusen 20th on eight points.

While Newcastle are 15th on nine points.

Leverkusen have also lost their last two games (all comps) coming into the game, whereas Newcastle head here off a 2-1 win over Burnley.

But Newcastle’s last six games ALL also saw OVER 2.5 GOALS, so this could be the way to play this one at 4/6.

BEST BET: OVER 2.5 GOALS @ 4/6

Match Odds

Benfica vs Napoli 20:00

Four past meetings between these two sides, with Napoli holding the edge with three wins, with just the one for Benfica.

They last met in 2016 in this competition, which resulted in a 2-1 away win for Napoli.

Three of the four H2H’s saw OVER 2.5 Goals, so there could be something here.

But Napoli come here having lost only one of their last 10 games and will know a win here will move them significantly up the table.

The Italian side are currently 22nd with seven points – but a win will see them move just outside the automatic qualification places.

BEST BET: NAPOLI TO WIN @ 2/1

Match Odds

Borussia Dortmund vs Bodø / Glimt 20:00

These sides have never played.

Dortmund are sitting 10th in the Champions League table on 10 points so a win will see them move into the qualification places.

Whereas Bodo/Glimt are struggling in 33rd (two points).

Dortmund also come here off a comfortable 2-0 home win over Hoffenheim last weekend.

So with home advantage too and a lot more to play for it’s hard to see anything but a Dortmund win here.

BEST BET: BORUSSIA DORTMUND TO WIN @ 4/11

Match Odds

Club Brugge vs Arsenal 20:00

Another first here as these sides are yet to play each other.

Club Brugge are sitting 27th (four points) and with games running out will know they will need a win here to keep their hopes alive of at least getting into the play-offs.

But they face Arsenal, who are flying high this season and have won all five games in the UCL.

Therefore, with only three games to go will also know another win here and they will certainly of a top eight finish.

However, the Gunners will be reeling after their recent 2-1 defeat to Villa, so will be looking to bounce back quickly.

On a plus though the London side will take on Club Brugge, who have won only one of their last four games.

This should be a comfortable away win for Arsenal – and a Champions League betting tip that can feature in many doubles, trebles and accas on Wednesday.

The 4/11 looks a tad skinny though, so we can boost these odds slightly with the 8/15 on the OVER 2.5 GOAL market.

BEST BET: OVER 2.5 GOALS @ 8/15

Match Odds

Juventus vs Pafos 20:00

These sides are yet to play each other too.

And as the betting suggests, this should be an easy win for Juventus, who are 23rd in the table on six points.

Which is actually the same as Pafos, who are just one place behind the Italian giants on goal difference.

Juventus lost to Napoli last weekend, but still come here having lost only one of their last nine.

But will face a Pafos side that are also in form – the Greek team are unbeaten in their last eight.

However, with home advantage it’s hard to see Juventus not bagging all three points here.

The 1/6 is too short, so try the 8/13 on them leading at both half-time and full-time.

BEST BET: HT/FT (Juventus/Juventus) @ 8/13

Match Odds

Real Madrid vs Manchester City 20:00

This will be the fifteenth time Real and City have played and the honours are fairly even.

Real have five wins, City four – with five draws. They last met in the UCL last season, with Real winning 3-1 and 3-2 in the knockout stages.

Despite being the away side City are also the 5/4 favourites in the match betting.

But Real are 6th in the table (12 points) and City 12th (10 points) – so a tricky game to call.

Both teams to score looks a banker, but that is reflected in the odds at 2/5. As is Over 2.5 Goals at 4/9.

They are also both right in the mix to make the next phase – so maybe the draw at 11/4 could be value.

That said, let’s play this one safe and opt for both teams to find the back of the net – short odds, but another that can be plonked into doubles, trebles and accas to boost returns.

BEST BET: BOTH TEAMS TO SCORE @ 2/5

Match Odds

 Note: All odds on this page are subject to change