The Carabao Cup returns this week as Premier League champions Liverpool host Championship Southampton at Anfield, and you can back our betting tips with this 18/1 bet builder.
It’s the third round of the League Cup on Tuesday, as two sides in different divisions and enjoying very different starts to the season face off.
Champions of England, Liverpool’s title defence has started perfectly, with five wins from five.
They also won 3-2 against Atletico Madrid in their opening UEFA Champions League fixture, with Virgil van Dijk’s late header clinching victory after the Reds were pegged back from 2-0 up.
Southampton, meanwhile, have just one league victory so far.
Their 2-1 win against promoted Wrexham feels like a very long time ago, and they were poor in defeat to Hull City on Saturday.
A 0-0 draw in the South Coast Derby left fans disappointed, and they will need to be much better if they are to avoid an embarrassing result on Merseyside.
Ahead of this one, Liverpool are 1/6 favourites with football betting sites, while Southampton are priced around 12/1.
We take on Southampton tomorrow in the Carabao Cup. pic.twitter.com/iSXBN23Y5W
— Liverpool FC (@LFC) September 22, 2025
Liverpool Vs Southampton Betting Tips
- Rio Ngumoha To Score Any Time @ 13/10
- Both Teams To Score – No @ 4/5 @
- Taylor Harwood-Bellis to be booked @ 10/3
Rio Ngumoha To Score Any Time @ 13/10
Our first pick is for Liverpool youngster Rio Ngumoha to score against the Saints.
The 17-year-old England youth international sensationally grabbed the winner for the Reds against Newcastle in stoppage time.
He has looked threatening every time he’s played this season, and with Arne Slot likely to rotate heavily, he has a good chance of a start on Tuesday.
Both Teams To Score – No @ 4/5
Next up, we can’t see Southampton scoring at Anfield.
The Saints have made a poor start to the season and have found goals hard to come by.
Fullback Ryan Manning is their only player with two league goals this season, both from free kicks.
Will Still’s rebuild project is in its infancy, and we feel Southampton are a long way off being able to threaten even a very understrength Liverpool side, especially at Anfield.
Taylor Harwood-Bellis to be booked @ 10/3
And finally, we predict Southampton defender Taylor Harwood-Bellis to pick up a booking if he plays.
Chelsea were interested in Harwood-Bellis over the summer, but the Manchester City academy graduate has remained at St. Marys.
He has so far picked up three yellow cards in five league games, and doesn’t shy away from a challenge, making him a good choice to pick up a yellow on Tuesday.
Back Our Liverpool Vs Southampton Betting Tips: 18/1 Carabao Cup Bet Builder
You can back any of these three tips individually, or combine them in to a 18/1 Carabao Cup Bet Builder.
Doing so means that placing a stake of £10 will return £190.
Liverpool Vs Southampton Betting Odds
| Match Result | Odds |
| Liverpool | 1/6 |
| Draw | 13/2 |
| Southampton | 12/1 |
| Player to Score at Any Time | Odds |
| Alexander Isak | 4/7 |
| Mohamed Salah | 4/6 |
| Hugo Ekitike | 8/11 |
| Jayden Danns | 20/21 |
| Cody Gakpo | 13/10 |
| Rio Ngumoha | 13/10 |
| Federico Chiesa | 8/5 |
| Florian Wirtz | 8/5 |
| Adam Armstrong | 7/2 |
| Cameron Archer | 9/2 |
