Premier League giants Manchester City and Tottenham go head-to-head in Saturday’s early kick-off, and we’ve got the latest team news and predicted lineups for the clash.
Saturday’s Premier League action gets underway with top-of-the-table Manchester City welcoming third-place Tottenham Hotspur to the Etihad, with kick-off scheduled for 12:30.
Both sides will be looking to build on the victories they secured on the opening weekend. The Cityzens defeated Wolves 4-0 on the road, and Spurs cruised to a 3-0 triumph over Burnley.
Erling Haaland and Richarlison were the stars of the show in their respective Gameweek 1 fixtures, with the pair netting a brace apiece to go joint-top of the division’s goalscoring charts.
Manchester City are odds-on favourites with UK betting sites to secure three points on Saturday, priced at around 1/2, while the visitors are rated at around 11/2 to pick up a shock victory.
As matchday and kick-off approach, we at SportsCasting have the latest team news and predicted lineups for the clash. Read on as we name the most probable XIs, along with providing updates on any injury or suspension concerns in both camps.
Manchester City vs Tottenham Team News and Predicted Lineups
Manchester City Team News
Pep Guardiola likes to switch things up in his lineups from one week to the next, but he’ll be without several key players for Spurs’ visit, with up to six potentially missing out through injury.
One of those is Mateo Kovacic, who remains sidelined with an achilles issue. According to reports, the Croatian is progressing in his recovery and should be back in contention in October.
Star midfielder Rodri is also set to miss out as he looks to fully recover from his ACL injury.
Seeing Rodri back with a smile brings joy to all of us! đ©”
Heâs been through a tough year! đȘđ» pic.twitter.com/YtCJ7PW0pY
â City Chief (@City_Chief) August 21, 2025
Elsewhere, Savinho, Claudio Echeverri and Josko Gvardiol are major doubts having missed last week’s win over Wolves. Phil Foden is a minor doubt due to an ankle problem.
Additionally, Ederson is set to be omitted from the squad amid links with a move to Galatasaray.
It comes following James Trafford’s arrival from Burnley this summer, while Manchester City are also being linked with Gianluigi Donnarumma from Paris Saint-Germain.
Manchester City Predicted Lineup (4-3-3):
Trafford (GK)
Lewis, Stones, Dias, Ait-Nouri
Reijnders, Gonzalez, Silva (C)
Bobb, Haaland, Doku
Tottenham Team News
On the road against one of the strongest teams in the league, Thomas Frank is expected to field a more defensive-minded lineup, similar to what was fielded in the Super Cup vs PSG.
With potential for a back five, Kevin Danso is tipped to come in as the additional defender. Despite a goal in the win over Burnley, Brennan Johnson could be the one that makes way.
Richarlison is likely to retain his place in the XI, likely joined by Mohammed Kudus in attack.
In terms of injury concerns, Spurs remain with a lengthy absentee list.
Radu Dragusin (ACL), James Maddison (ACL), Dejan Kulusevski (knee), Bryan Gil (knee), Kota Takai (ankle), Yves Bissouma (unknown) and Manor Solomon (calf) have all been ruled out.
Destiny Udogie is still a doubt as he continues to progress in his recovery from a knee issue.
Tottenham Predicted Lineup (5-3-2):
Vicario (GK)
Porro, Romero, Danso, Van de Ven, Spence
Bergvall, Bentancur, Sarr
Kudus, Richarlison
